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[207], who demonstrated the peptide to induce a potent and long-lasting opioid antinociceptive effect in neuropathic pain induced in rats by chronic constriction of the sciatic nerve, as it was blocked by naloxone, an opioid receptor antagonist
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In addition, hydrochlorothiazide, bumetanide and furosemide were also consistently linked to altered blood glucose and impaired glucose tolerance in a variety of animal models (Foy, 1967
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