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Chronic activation of AMPK by Hirsutine is also associated with GLUT4 translocation in muscle tissue, which contributes to improved glucose regulation (Hu et al., 2022)
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CS induces S-glutathionylation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH), leading to its inactivation, reduced ECAR, decreased ATP production, and impaired pyruvate generation (40)
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