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The accumulation of metal ions promotes the production of hydrogen peroxide and hydroxyl radical through Fenton and Haber-Weiss reactions, resulting in lipid peroxidation of cell membrane (von Krusenstiern et al., 2023)

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In summary, our results indicate that thiols may alter AX availability, both in vitro and in cellular environments, thus constituting a major determinant for AX action under pathophysiological conditions

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