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Consistent with enhanced mitochondrial oxidative stress, immunofluorescence staining revealed visibly higher levels of nitrotyrosine adducts in HuR Hep-/- male mouse livers compared with WT at 2 hours post-overdose (Figure 6C)
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It is noticeable here that oleylcarnitine (C18:1) decreased significantly in the patients (0.7 ± 0.21 µmol/L) compared to the healthy controls (0.81 ± 0.25 µmol/L), generating a P-value of 0.007
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